human OFD1 shRNA silencing AAV

Cat. No: shAAV-217372

Availability: 4-5 weeks

Name: AAV-h-OFD1-shRNA

This is an AAV expressing shRNA for silencing of Human OFD1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: OFD1
Gene Name: OFD1, centriole and centriolar satellite protein
Gene ID: 8481
Gene Synonyms: 71-7A; CXorf5; JBTS10; RP23; SGBS2
ORF Size: 2919 bp
RefSeq#: NM_003611
Gene Description: OFD1 is located on the X chromosome and encodes a centrosomal protein. A knockout mouse model has been used to study the effect of mutations in this gene. The mouse gene is also located on the X chromosome, however, unlike the human gene it is not subject to X inactivation. Mutations in this gene are associated with oral-facial-digital syndrome type I and Simpson-Golabi-Behmel syndrome type 2. Many pseudogenes have been identified; a single pseudogene is found on chromosome 5 while as many as fifteen have been found on the Y chromosome. Alternatively spliced transcripts have been described for this gene but the biological validity of these transcripts has not been determined.
UniGene ID: Hs.6483
HGNC ID: HGNC:2567