human OCRL shRNA silencing AAV

Cat. No: shAAV-217345

Availability: 4-5 weeks

Name: AAV-h-OCRL-shRNA

This is an AAV expressing shRNA for silencing of Human OCRL.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: OCRL
Gene Name: OCRL, inositol polyphosphate-5-phosphatase
Gene ID: 4952
Gene Synonyms: INPP5F; LOCR; NPHL2; OCRL-1; OCRL1
ORF Size: 2682 bp
RefSeq#: NM_000276
Gene Description: OCRL encodes a phosphatase enzyme that is involved in actin polymerization and is found in the trans-Golgi network. Mutations in this gene cause oculocerebrorenal syndrome of Lowe and also Dent disease.
UniGene ID: Hs.126357
HGNC ID: HGNC:8108