human NUDCD3 shRNA silencing AAV

Cat. No: shAAV-217195

Availability: 4-5 weeks

Name: AAV-h-NUDCD3-shRNA

This is an AAV expressing shRNA for silencing of Human NUDCD3.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: NUDCD3
Gene Name: NudC domain containing 3
Gene ID: 23386
Gene Synonyms: NudCL
ORF Size: 1086 bp
RefSeq#: NM_015332
Gene Description: The product of this gene functions to maintain the stability of dynein intermediate chain. Depletion of this gene product results in aggregation and degradation of dynein intermediate chain, mislocalization of the dynein complex from kinetochores, spindle microtubules, and spindle poles, and loss of gamma-tubulin from spindle poles. The protein localizes to the Golgi apparatus during interphase, and levels of the protein increase after the G1/S transition.
UniGene ID: Hs.488171
HGNC ID: HGNC:22208