human NR4A1 shRNA silencing AAV

Cat. No: shAAV-217056

Availability: 4-5 weeks

Name: AAV-h-NR4A1-shRNA

This is an AAV expressing shRNA for silencing of Human NR4A1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: NR4A1
Gene Name: nuclear receptor subfamily 4 group A member 1
Gene ID: 3164
Gene Synonyms: GFRP1; HMR; N10; NAK-1; NGFIB; NP10; NUR77; TR3
ORF Size: 1797 bp
RefSeq#: NM_002135
Gene Description: NR4A1 encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.524430
HGNC ID: HGNC:7980