human NR2E3 shRNA silencing AAV

Cat. No: shAAV-217048

Availability: 6-8 weeks

Name: AAV-h-NR2E3-shRNA

This is an AAV expressing shRNA for silencing of Human NR2E3.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: NR2E3
Gene Name: nuclear receptor subfamily 2 group E member 3
Gene ID: 10002
Gene Synonyms: ESCS; PNR; rd7; RNR; RP37
ORF Size: 969 bp
RefSeq#: NM_014249
Gene Description: This protein is part of a large family of nuclear receptor transcription factors involved in signaling pathways. Nuclear receptors have been shown to regulate pathways involved in embryonic development, as well as in maintenance of proper cell function in adults. Members of this family are characterized by discrete domains that function in DNA and ligand binding. This gene encodes a retinal nuclear receptor that is a ligand-dependent transcription factor. Defects in this gene are a cause of enhanced S cone syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
UniGene ID: Hs.187354
HGNC ID: HGNC:7974