human NPL shRNA silencing AAV

Cat. No: shAAV-216971

Availability: 4-5 weeks

Name: AAV-h-NPL-shRNA

This is an AAV expressing shRNA for silencing of Human NPL.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: NPL
Gene Name: N-acetylneuraminate pyruvate lyase
Gene ID: 80896
Gene Synonyms: C112; C1orf13; NAL; NPL1
ORF Size: 963 bp
RefSeq#: NM_030769
Gene Description: NPL encodes a member of the N-acetylneuraminate lyase sub-family of (beta/alpha)(8)-barrel enzymes. N-acetylneuraminate lyases regulate cellular concentrations of N-acetyl-neuraminic acid (sialic acid) by mediating the reversible conversion of sialic acid into N-acetylmannosamine and pyruvate. A pseudogene of this gene is located on the short arm of chromosome 2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
UniGene ID: Hs.496969
HGNC ID: HGNC:16781