human NOX1 shRNA silencing AAV

Cat. No: shAAV-216922

Availability: 6-8 weeks

Name: AAV-h-NOX1-shRNA

This is an AAV expressing shRNA for silencing of Human NOX1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: NOX1
Gene Name: NADPH oxidase 1
Gene ID: 27035
Gene Synonyms: GP91-2; MOX1; NOH-1; NOH1
ORF Size: 1695 bp
RefSeq#: NM_007052
Gene Description: Voltage-gated proton (hydrogen) channels play an important role in cellular defense against acidic stress. They are unique among ion channels with respect to their extremely high selectivity, marked temperature dependence, and unitary conductance, which is 3 orders of magnitude lower than that of most other ion channels. NOX1 is a homolog of the catalytic subunit of the superoxide-generating NADPH oxidase of phagocytes, gp91phox. Two transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.592227
HGNC ID: HGNC:7889