human NLRP12 shRNA silencing AAV

Cat. No: shAAV-216793

Availability: 6-8 weeks

Name: AAV-h-NLRP12-shRNA

This is an AAV expressing shRNA for silencing of Human NLRP12.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: NLRP12
Gene Name: NLR family pyrin domain containing 12
Gene ID: 91662
Gene Synonyms: CLR19.3; FCAS2; NALP12; PAN6; PYPAF7; RNO; RNO2
ORF Size: 3186 bp
RefSeq#: NM_144687
Gene Description: NLRP12 encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Alternatively spliced transcript variants encoding distinct isoforms have been described but the full-length nature of some of these has not been determined.
UniGene ID: Hs.631573
HGNC ID: HGNC:22938