human NFYB shRNA silencing AAV

Cat. No: shAAV-216665

Availability: 4-5 weeks

Name: AAV-h-NFYB-shRNA

This is an AAV expressing shRNA for silencing of Human NFYB.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: NFYB
Gene Name: nuclear transcription factor Y subunit beta
Gene ID: 4801
Gene Synonyms: CBF-A; CBF-B; HAP3; NF-YB
ORF Size: 624 bp
RefSeq#: NM_006166
Gene Description: NFYB is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit B, forms a tight dimer with the C subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence; protein sequence alignments and experiments with mutants.
UniGene ID: Hs.84928
HGNC ID: HGNC:7805