human NFKBIB shRNA silencing AAV

Cat. No: shAAV-216649

Availability: 4-5 weeks

Name: AAV-h-NFKBIB-shRNA

This is an AAV expressing shRNA for silencing of Human NFKBIB.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: NFKBIB
Gene Name: NFKB inhibitor beta
Gene ID: 4793
Gene Synonyms: IKBB; TRIP9
ORF Size: 1071 bp
RefSeq#: NM_002503
Gene Description: NFKBIB belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.
UniGene ID: Hs.9731
HGNC ID: HGNC:7798