human NEK8 shRNA silencing AAV

Cat. No: shAAV-216576

Availability: 6-8 weeks

Name: AAV-h-NEK8-shRNA

This is an AAV expressing shRNA for silencing of Human NEK8.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: NEK8
Gene Name: NIMA related kinase 8
Gene ID: 284086
Gene Synonyms: JCK; NEK12A; NPHP9; RHPD2
ORF Size: 2079 bp
RefSeq#: NM_178170
Gene Description: NEK8 encodes a member of the serine/threionine protein kinase family related to NIMA (never in mitosis, gene A) of Aspergillus nidulans. The encoded protein may play a role in cell cycle progression from G2 to M phase. Mutations in the related mouse gene are associated with a disease phenotype that closely parallels the juvenile autosomal recessive form of polycystic kidney disease in humans.
UniGene ID: Hs.448468
HGNC ID: HGNC:13387