human NCKIPSD shRNA silencing AAV

Cat. No: shAAV-216406

Availability: 4-5 weeks

Name: AAV-h-NCKIPSD-shRNA

This is an AAV expressing shRNA for silencing of Human NCKIPSD.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: NCKIPSD
Gene Name: NCK interacting protein with SH3 domain
Gene ID: 51517
Gene Synonyms: AF3P21; DIP; DIP1; ORF1; SPIN90; VIP54; WASLBP; WISH
ORF Size: 2148 bp
RefSeq#: NM_016453
Gene Description: NCKIPSD is localized exclusively in the cell nucleus. It plays a role in signal transduction, and may function in the maintenance of sarcomeres and in the assembly of myofibrils into sarcomeres. It also plays an important role in stress fiber formation. The gene is involved in therapy-related leukemia by a chromosomal translocation t(3;11)(p21;q23) that involves this gene and the myeloid/lymphoid leukemia gene. Alternative splicing occurs in this locus and two transcript variants encoding distinct isoforms have been identified.
UniGene ID: Hs.655006
HGNC ID: HGNC:15486