human NCKAP1L shRNA silencing AAV

Cat. No: shAAV-216404

Availability: 6-8 weeks

Name: AAV-h-NCKAP1L-shRNA

This is an AAV expressing shRNA for silencing of Human NCKAP1L.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: NCKAP1L
Gene Name: NCK associated protein 1 like
Gene ID: 3071
Gene Synonyms: HEM1
ORF Size: 3384 bp
RefSeq#: NM_005337
Gene Description: NCKAP1L encodes a member of the HEM family of tissue-specific transmembrane proteins which are highly conserved from invertebrates through mammals. NCKAP1L is only expressed in hematopoietic cells. The encoded protein is a part of the Scar/WAVE complex which plays an important role in regulating cell shape in both metazoans and plants. Alternatively spliced transcript variants encoding different isoforms have been found.
UniGene ID: Hs.182014
HGNC ID: HGNC:4862