human NAT8B shRNA silencing AAV

Cat. No: shAAV-216350

Availability: 6-8 weeks

Name: AAV-h-NAT8B-shRNA

This is an AAV expressing shRNA for silencing of Human NAT8B.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: NAT8B
Gene Name: N-acetyltransferase 8B (putative, gene/pseudogene)
Gene ID: 51471
Gene Synonyms: CML2; Hcml2; NAT8BP
ORF Size: 684 bp
RefSeq#: NM_016347
Gene Description: NAT8B is highly similar to the N-acetyltransferase 8 (NAT8) gene product, which is a kidney and liver protein with homology to bacterial acetyltransferases involved in drug resistance. This gene is localized on chromosome 2 in the vicinity of the NAT8 gene and may represent a pseudogene of NAT8. This gene contains two polymorphic nonsense mutations that disrupt the active site of the protein. The full-length product of this gene contains a complete acetyltransferase domain and is identical in length to NAT8.
UniGene ID: Hs.458287
HGNC ID: HGNC:30235