human MYOCD shRNA silencing AAV

Cat. No: shAAV-216227

Availability: 6-8 weeks

Name: AAV-h-MYOCD-shRNA

This is an AAV expressing shRNA for silencing of Human MYOCD.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: MYOCD
Gene Name: myocardin
Gene ID: 93649
Gene Synonyms: MYCD
ORF Size: 2961 bp
RefSeq#: NM_153604
Gene Description: MYOCD encodes a nuclear protein, which is expressed in heart, aorta, and in smooth muscle cell-containing tissues. It functions as a transcriptional co-activator of serum response factor (SRF) and modulates expression of cardiac and smooth muscle-specific SRF-target genes, and thus may play a crucial role in cardiogenesis and differentiation of the smooth muscle cell lineage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.567641
HGNC ID: HGNC:16067