human MYO1E shRNA silencing AAV

Cat. No: shAAV-216212

Availability: 4-5 weeks

Name: AAV-h-MYO1E-shRNA

This is an AAV expressing shRNA for silencing of Human MYO1E.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: MYO1E
Gene Name: myosin IE
Gene ID: 4643
Gene Synonyms: FSGS6; HuncM-IC; MYO1C
ORF Size: 3327 bp
RefSeq#: NM_004998
Gene Description: MYO1E encodes a member of the nonmuscle class I myosins which are a subgroup of the unconventional myosin protein family. The unconventional myosin proteins function as actin-based molecular motors. Class I myosins are characterized by a head (motor) domain, a regulatory domain and a either a short or long tail domain. Among the class I myosins, this protein is distinguished by a long tail domain that is involved in crosslinking actin filaments. This protein localizes to the cytoplasm and may be involved in intracellular movement and membrane trafficking. Mutations in this gene are the cause of focal segmental glomerulosclerosis-6. MYO1E has been referred to as myosin IC in the literature but is distinct from the myosin IC gene located on chromosome 17.
UniGene ID: Hs.654506
HGNC ID: HGNC:7599