human MYL2 shRNA silencing AAV

Cat. No: shAAV-216181

Availability: 6-8 weeks

Name: AAV-h-MYL2-shRNA

This is an AAV expressing shRNA for silencing of Human MYL2.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: MYL2
Gene Name: myosin light chain 2
Gene ID: 4633
Gene Synonyms: CMH10; MLC-2s/v; MLC2
ORF Size: 501 bp
RefSeq#: NM_000432
Gene Description: Thus gene encodes the regulatory light chain associated with cardiac myosin beta (or slow) heavy chain. Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. Mutations in this gene are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy.
UniGene ID: Hs.75535
HGNC ID: HGNC:7583