human MYH8 shRNA silencing AAV

Cat. No: shAAV-216172

Availability: 6-8 weeks

Name: AAV-h-MYH8-shRNA

This is an AAV expressing shRNA for silencing of Human MYH8.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: MYH8
Gene Name: myosin heavy chain 8
Gene ID: 4626
Gene Synonyms: DA7; gtMHC-F; MyHC-peri; MyHC-pn
ORF Size: 5814 bp
RefSeq#: NM_002472
Gene Description: Myosins are actin-based motor proteins that function in the generation of mechanical force in eukaryotic cells. Muscle myosins are heterohexamers composed of 2 myosin heavy chains and 2 pairs of nonidentical myosin light chains. This gene encodes a member of the class II or conventional myosin heavy chains, and functions in skeletal muscle contraction. This gene is predominantly expressed in fetal skeletal muscle. This gene is found in a cluster of myosin heavy chain genes on chromosome 17. A mutation in this gene results in trismus-pseudocamptodactyly syndrome.
UniGene ID: Hs.700484
HGNC ID: HGNC:7578