human MSX2 shRNA silencing AAV

Cat. No: shAAV-215942

Availability: 4-5 weeks

Name: AAV-h-MSX2-shRNA

This is an AAV expressing shRNA for silencing of Human MSX2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: MSX2
Gene Name: msh homeobox 2
Gene ID: 4488
Gene Synonyms: CRS2; FPP; HOX8; MSH; PFM; PFM1
ORF Size: 804 bp
RefSeq#: NM_002449
Gene Description: MSX2 encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2.
UniGene ID: Hs.89404
HGNC ID: HGNC:7392