human GPLD1 shRNA silencing AAV

Cat. No: shAAV-215879

Availability: 6-8 weeks

Name: AAV-h-GPLD1-shRNA

This is an AAV expressing shRNA for silencing of Human GPLD1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: GPLD1
Gene Name: glycosylphosphatidylinositol specific phospholipase D1
Gene ID: 2822
Gene Synonyms: GPIPLD; GPIPLDM; MGC22590; PIGPLD; PIGPLD1;
ORF Size: 2523 bp
RefSeq#: NM_001503
Gene Description: Many proteins are tethered to the extracellular face of eukaryotic plasma membranes by a glycosylphosphatidylinositol (GPI) anchor. The GPI-anchor is a glycolipid found on many blood cells. The protein encoded by this gene is a GPI degrading enzyme. Glycosylphosphatidylinositol specific phospholipase D1 hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans, thereby releasing the attached protein from the plasma membrane.
UniGene ID: Hs.533291
HGNC ID: HGNC:4459