human MPP6 shRNA silencing AAV

Cat. No: shAAV-215724

Availability: 4-5 weeks

Name: AAV-h-MPP6-shRNA

This is an AAV expressing shRNA for silencing of Human MPP6.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: MPP6
Gene Name: membrane palmitoylated protein 6
Gene ID: 51678
Gene Synonyms: p55T; PALS2; VAM-1; VAM1
ORF Size: 1623 bp
RefSeq#: NM_016447
Gene Description: Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal, and cytoplasmic signaling proteins. All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies, DLG-like (see DLG1; MIM 601014), ZO1-like (see TJP1; MIM 601009), p55-like (see MPP1; MIM 305360), and LIN2-like (see CASK; MIM 300172), based on their size and the presence of additional domains. MPP6 is a member of the p55-like MAGUK subfamily (Tseng et al., 2001 (PubMed 11311936)).(supplied by OMIM, Mar 2008)
UniGene ID: Hs.533355
HGNC ID: HGNC:18167