human MOCS2 shRNA silencing AAV

Cat. No: shAAV-215630

Availability: 4-5 weeks

Name: AAV-h-MOCS2-shRNA

This is an AAV expressing shRNA for silencing of Human MOCS2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: MOCS2
Gene Name: molybdenum cofactor synthesis 2
Gene ID: 4338
Gene Synonyms: MCBPE; MOCO1; MOCODB; MPTS
ORF Size: 567 bp
RefSeq#: NM_004531
Gene Description: Eukaryotic molybdoenzymes use a unique molybdenum cofactor (MoCo) consisting of a pterin, termed molybdopterin, and the catalytically active metal molybdenum. MoCo is synthesized from precursor Z by the heterodimeric enzyme molybdopterin synthase. The large and small subunits of molybdopterin synthase are both encoded from this gene by overlapping open reading frames. The proteins were initially thought to be encoded from a bicistronic transcript. They are now thought to be encoded from monocistronic transcripts. Alternatively spliced transcripts have been found for this locus that encode the large and small subunits.
UniGene ID: Hs.163645
HGNC ID: HGNC:7193