human MMP17 shRNA silencing AAV

Cat. No: shAAV-215582

Availability: 4-5 weeks

Name: AAV-h-MMP17-shRNA

This is an AAV expressing shRNA for silencing of Human MMP17.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: MMP17
Gene Name: matrix metallopeptidase 17
Gene ID: 4326
Gene Synonyms: MMP-17; MT4-MMP; MT4MMP; MTMMP4
ORF Size: 1821 bp
RefSeq#: NM_016155
Gene Description: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene is considered a member of the membrane-type MMP (MT-MMP) subfamily. However, this protein is unique among the MT-MMP's in that it is a GPI-anchored protein rather than a transmembrane protein. The protein activates MMP-2 by cleavage.
UniGene ID: Hs.709245
HGNC ID: HGNC:7163