human MINPP1 shRNA silencing AAV

Cat. No: shAAV-215475

Availability: 4-5 weeks

Name: AAV-h-MINPP1-shRNA

This is an AAV expressing shRNA for silencing of Human MINPP1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: MINPP1
Gene Name: multiple inositol-polyphosphate phosphatase 1
Gene ID: 9562
Gene Synonyms: HIPER1; MINPP2; MIPP
ORF Size: 1464 bp
RefSeq#: NM_004897
Gene Description: MINPP1 encodes multiple inositol polyphosphate phosphatase; an enzyme that removes 3-phosphate from inositol phosphate substrates. It is the only enzyme known to hydrolzye inositol pentakisphosphate and inositol hexakisphosphate. This enzyme also converts 2,3 bisphosphoglycerate (2,3-BPG) to 2-phosphoglycerate; an activity formerly thought to be exclusive to 2,3-BPG synthase/2-phosphatase (BPGM) in the Rapoport-Luebering shunt of the glycolytic pathway.
UniGene ID: Hs.121260
HGNC ID: HGNC:7102