human MET shRNA silencing AAV

Cat. No: shAAV-215319

Availability: 4-5 weeks

Name: AAV-h-MET-shRNA

This is an AAV expressing shRNA for silencing of Human MET.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: MET
Gene Name: MET proto-oncogene, receptor tyrosine kinase
Gene ID: 4233
Gene Synonyms: AUTS9; c-Met; DFNB97; HGFR; RCCP2
ORF Size: 4173 bp
RefSeq#: NM_000245
Gene Description: The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.132966
HGNC ID: HGNC:7029