human MEN1 shRNA silencing AAV

Cat. No: shAAV-215297

Availability: 4-5 weeks

Name: AAV-h-MEN1-shRNA

This is an AAV expressing shRNA for silencing of Human MEN1.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: MEN1
Gene Name: menin 1
Gene ID: 4221
Gene Synonyms: MEAI; SCG2
ORF Size: 1728 bp
RefSeq#: NM_000244
Gene Description: MEN1 encodes menin, a putative tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. In vitro studies have shown menin is localized to the nucleus, possesses two functional nuclear localization signals, and inhibits transcriptional activation by JunD, however, the function of this protein is not known. Two messages have been detected on northern blots but the larger message has not been characterized. Alternative splicing results in multiple transcript variants.
UniGene ID: Hs.423348
HGNC ID: HGNC:7010