human MEF2C shRNA silencing AAV

Cat. No: shAAV-215273

Availability: 4-5 weeks

Name: AAV-h-MEF2C-shRNA

This is an AAV expressing shRNA for silencing of Human MEF2C.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: MEF2C
Gene Name: myocyte enhancer factor 2C
Gene ID: 4208
Gene Synonyms: C5DELq14.3; DEL5q14.3
ORF Size: 1419 bp
RefSeq#: NM_002397
Gene Description: This locus encodes a member of the MADS box transcription enhancer factor 2 (MEF2) family of proteins, which play a role in myogenesis. The encoded protein, MEF2 polypeptide C, has both trans-activating and DNA binding activities. This protein may play a role in maintaining the differentiated state of muscle cells. Mutations and deletions at this locus have been associated with severe mental retardation, stereotypic movements, epilepsy, and cerebral malformation. Alternatively spliced transcript variants have been described.
UniGene ID: Hs.653394
HGNC ID: HGNC:6996