human MED21 shRNA silencing AAV

Cat. No: shAAV-215253

Availability: 4-5 weeks

Name: AAV-h-MED21-shRNA

This is an AAV expressing shRNA for silencing of Human MED21.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: MED21
Gene Name: mediator complex subunit 21
Gene ID: 9412
Gene Synonyms: hSrb7; SRB7; SURB7
ORF Size: 435 bp
RefSeq#: NM_004264
Gene Description: The Mediator is a multiprotein coactivator that is required by DNA-binding transcription factors for transcriptional activation of polymerase II (see MIM 180660)-transcribed genes. MED21 is a Mediator subunit predicted to reside in the middle module and appears to be a core subunit found in nearly all Mediator preparations (summary by Sato et al., 2004 (PubMed 15175163)).(supplied by OMIM, Nov 2010)
UniGene ID: Hs.286145
HGNC ID: HGNC:11473