human MED13 shRNA silencing AAV

Cat. No: shAAV-215237

Availability: 4-5 weeks

Name: AAV-h-MED13-shRNA

This is an AAV expressing shRNA for silencing of Human MED13.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: MED13
Gene Name: mediator complex subunit 13
Gene ID: 9969
Gene Synonyms: ARC250; DRIP250; HSPC221; THRAP1; TRAP240
ORF Size: 6525 bp
RefSeq#: NM_005121
Gene Description: MED13 encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. The product of this gene is proposed to form a sub-complex with MED12, cyclin C, and CDK8 that can negatively regulate transactivation by mediator.
UniGene ID: Hs.282678
HGNC ID: HGNC:22474