human MCOLN3 shRNA silencing AAV

Cat. No: shAAV-215200

Availability: 6-8 weeks

Name: AAV-h-MCOLN3-shRNA

This is an AAV expressing shRNA for silencing of Human MCOLN3.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: MCOLN3
Gene Name: mucolipin 3
Gene ID: 55283
Gene Synonyms: TRP-ML3; TRPML3
ORF Size: 966 bp
RefSeq#: NM_018298
Gene Description: MCOLN3 encodes one of members of the mucolipin cation channel proteins. Mutation studies of the highly similar protein in mice have shown that the protein is found in cochlea hair cells, and mutant mice show early-onset hearing loss and balance problems. Multiple transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.535239
HGNC ID: HGNC:13358