human MCM3AP shRNA silencing AAV

Cat. No: shAAV-215183

Availability: 4-5 weeks

Name: AAV-h-MCM3AP-shRNA

This is an AAV expressing shRNA for silencing of Human MCM3AP.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: MCM3AP
Gene Name: minichromosome maintenance complex component 3 associated protein
Gene ID: 8888
Gene Synonyms: GANP; MAP80; SAC3
ORF Size: 5943 bp
RefSeq#: NM_003906
Gene Description: The minichromosome maintenance protein 3 (MCM3) is one of the MCM proteins essential for the initiation of DNA replication. The protein encoded by this gene is a MCM3 binding protein. It was reported to have phosphorylation-dependent DNA-primase activity, which was up-regulated in antigen immunization induced germinal center. This protein was demonstrated to be an acetyltransferase that acetylates MCM3 and plays a role in DNA replication. The mutagenesis of a nuclear localization signal of MCM3 affects the binding of this protein with MCM3, suggesting that this protein may also facilitate MCM3 nuclear localization.
UniGene ID: Hs.389037
HGNC ID: HGNC:6946