human MCCC1 shRNA silencing AAV

Cat. No: shAAV-215157

Availability: 4-5 weeks

Name: AAV-h-MCCC1-shRNA

This is an AAV expressing shRNA for silencing of Human MCCC1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: MCCC1
Gene Name: methylcrotonoyl-CoA carboxylase 1
Gene ID: 56922
Gene Synonyms: MCC-B; MCCA
ORF Size: 2178 bp
RefSeq#: NM_020166
Gene Description: MCCC1 encodes the large subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA. Mutations in this gene are associated with 3-Methylcrotonylglycinuria, an autosomal recessive disorder of leucine catabolism.
UniGene ID: Hs.47649
HGNC ID: HGNC:6936