human MC2R shRNA silencing AAV

Cat. No: shAAV-215132

Availability: 6-8 weeks

Name: AAV-h-MC2R-shRNA

This is an AAV expressing shRNA for silencing of Human MC2R.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: MC2R
Gene Name: melanocortin 2 receptor
Gene ID: 4158
Gene Synonyms: ACTHR
ORF Size: 894 bp
RefSeq#: NM_000529
Gene Description: MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency.
UniGene ID: Hs.248144
HGNC ID: HGNC:6930