human MARK2 shRNA silencing AAV

Cat. No: shAAV-215037

Availability: 4-5 weeks

Name: AAV-h-MARK2-shRNA

This is an AAV expressing shRNA for silencing of Human MARK2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: MARK2
Gene Name: microtubule affinity regulating kinase 2
Gene ID: 2011
Gene Synonyms: EMK-1; EMK1; PAR-1; Par-1b; Par1b
ORF Size: 2175 bp
RefSeq#: NM_004954
Gene Description: MARK2 encodes a member of the Par-1 family of serine/threonine protein kinases. The protein is an important regulator of cell polarity in epithelial and neuronal cells, and also controls the stability of microtubules through phosphorylation and inactivation of several microtubule-associating proteins. The protein localizes to cell membranes. Multiple transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.567261
HGNC ID: HGNC:3332