human MAP4K5 shRNA silencing AAV

Cat. No: shAAV-214954

Availability: 6-8 weeks

Name: AAV-h-MAP4K5-shRNA

This is an AAV expressing shRNA for silencing of Human MAP4K5.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: MAP4K5
Gene Name: mitogen-activated protein kinase kinase kinase kinase 5
Gene ID: 11183
Gene Synonyms: GCKR; KHS; KHS1; MAPKKKK5
ORF Size: 2541 bp
RefSeq#: NM_006575
Gene Description: MAP4K5 encodes a member of the serine/threonine protein kinase family, that is highly similar to yeast SPS1/STE20 kinase. Yeast SPS1/STE20 functions near the beginning of the MAP kinase signal cascades that is essential for yeast pheromone response. This kinase was shown to activate Jun kinase in mammalian cells, which suggested a role in stress response. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.
UniGene ID: Hs.130491
HGNC ID: HGNC:6867