human MAP3K14 shRNA silencing AAV

Cat. No: shAAV-214928

Availability: 6-8 weeks

Name: AAV-h-MAP3K14-shRNA

This is an AAV expressing shRNA for silencing of Human MAP3K14.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: MAP3K14
Gene Name: mitogen-activated protein kinase kinase kinase 14
Gene ID: 9020
Gene Synonyms: FTDCR1B; HS; HSNIK; NIK
ORF Size: 2844 bp
RefSeq#: NM_003954
Gene Description: MAP3K14 encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor.
UniGene ID: Hs.404183
HGNC ID: HGNC:6853