human MAP2K6 shRNA silencing AAV

Cat. No: shAAV-214921

Availability: 4-5 weeks

Name: AAV-h-MAP2K6-shRNA

This is an AAV expressing shRNA for silencing of Human MAP2K6.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: MAP2K6
Gene Name: mitogen-activated protein kinase kinase 6
Gene ID: 5608
Gene Synonyms: MAPKK6; MEK6; MKK6; PRKMK6; SAPKK-3; SAPKK3
ORF Size: 1005 bp
RefSeq#: NM_002758
Gene Description: MAP2K6 encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.
UniGene ID: Hs.463978
HGNC ID: HGNC:6846