human MAGEE1 shRNA silencing AAV

Cat. No: shAAV-214841

Availability: 6-8 weeks

Name: AAV-h-MAGEE1-shRNA

This is an AAV expressing shRNA for silencing of Human MAGEE1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: MAGEE1
Gene Name: MAGE family member E1
Gene ID: 57692
Gene Synonyms: DAMAGE; HCA1
ORF Size: 2874 bp
RefSeq#: NM_020932
Gene Description: MAGEE1 encodes an alpha-dystrobrevin-associated MAGE (melanoma-associated antigen) protein, which is a member of the MAGE family. The protein contains a nuclear localization signal in the N-terminus, 30 12-amino acid repeats beginning at nt 60 with the consensus sequence ASEGPSTSVLPT, and two MAGE domains in the C-terminus. It may play a signaling role in brain, muscle, and peripheral nerve. MAGEE1 is located on X chromosome in a region containing loci linked to mental retardation.
UniGene ID: Hs.8453
HGNC ID: HGNC:24934