human MAGED1 shRNA silencing AAV

Cat. No: shAAV-214838

Availability: 4-5 weeks

Name: AAV-h-MAGED1-shRNA

This is an AAV expressing shRNA for silencing of Human MAGED1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: MAGED1
Gene Name: MAGE family member D1
Gene ID: 9500
Gene Synonyms: DLXIN-1; NRAGE
ORF Size: 2337 bp
RefSeq#: NM_006986
Gene Description: MAGED1 is a member of the melanoma antigen gene (MAGE) family. Most of the genes of this family encode tumor specific antigens that are not expressed in normal adult tissues except testis. Although the protein encoded by this gene shares strong homology with members of the MAGE family, it is expressed in almost all normal adult tissues. MAGED1 has been demonstrated to be involved in the p75 neurotrophin receptor mediated programmed cell death pathway. Three transcript variants encoding two different isoforms have been found for this gene.
UniGene ID: Hs.5258
HGNC ID: HGNC:6813