human MAGEB2 shRNA silencing AAV

Cat. No: shAAV-214826

Availability: 6-8 weeks

Name: AAV-h-MAGEB2-shRNA

This is an AAV expressing shRNA for silencing of Human MAGEB2.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: MAGEB2
Gene Name: MAGE family member B2
Gene ID: 4113
Gene Synonyms: CT3.2; DAM6; MAGE-XP-2
ORF Size: 960 bp
RefSeq#: NM_002364
Gene Description: MAGEB2 is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. MAGEB2 is localized in the DSS (dosage-sensitive sex reversal) critical region. It is expressed in testis and placenta, and in a significant fraction of tumors of various histological types. The MAGEB genes are clustered on chromosome Xp22-p21.
UniGene ID: Hs.113824
HGNC ID: HGNC:6809