human MADCAM1 shRNA silencing AAV

Cat. No: shAAV-214782

Availability: 6-8 weeks

Name: AAV-h-MADCAM1-shRNA

This is an AAV expressing shRNA for silencing of Human MADCAM1.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: MADCAM1
Gene Name: mucosal vascular addressin cell adhesion molecule 1
Gene ID: 8174
Gene Synonyms: MACAM1
ORF Size: 888 bp
RefSeq#: NM_130760
Gene Description: MADCAM1 is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4beta7), L-selectin, and VLA-4 (alpha4beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin family and is similar to ICAM1 and VCAM1. At least seven alternatively spliced transcripts encoding different protein isoforms have been found for this gene, but the full-length nature of some variants has not been determined.
UniGene ID: Hs.102598
HGNC ID: HGNC:6765