human LRRC2 shRNA silencing AAV

Cat. No: shAAV-214528

Availability: 6-8 weeks

Name: AAV-h-LRRC2-shRNA

This is an AAV expressing shRNA for silencing of Human LRRC2.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: LRRC2
Gene Name: leucine rich repeat containing 2
Gene ID: 79442
ORF Size: 1116 bp
RefSeq#: NM_024512
Gene Description: LRRC2 encodes a member of the leucine-rich repeat-containing family of proteins, which function in diverse biological pathways. This family member may possibly be a nuclear protein. Similarity to the RAS suppressor protein, as well as expression down-regulation observed in tumor cells, suggests that it may function as a tumor suppressor. The gene is located in the chromosome 3 common eliminated region 1 (C3CER1), a 1.4 Mb region that is commonly deleted in diverse tumors. A related pseudogene has been identified on chromosome 2.
UniGene ID: Hs.657345
HGNC ID: HGNC:14676