human GPBP1 shRNA silencing AAV

Cat. No: shAAV-214251

Availability: 4-5 weeks

Name: AAV-h-GPBP1-shRNA

This is an AAV expressing shRNA for silencing of Human GPBP1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: GPBP1
Gene Name: GC-rich promoter binding protein 1
Gene ID: 65056
Gene Synonyms: GPBP; SSH6; VASCULIN
ORF Size: 1422 bp
RefSeq#: NM_022913
Gene Description: GPBP1 was originally isolated by subtractive hybridization of cDNAs expressed in atherosclerotic plaques with a thrombus, and was found to be expressed only in vascular smooth muscle cells. However, a shorter splice variant was found to be more ubiquitously expressed. This protein is suggested to play a role in the development of atherosclerosis. Studies in mice suggest that it may also function as a GC-rich promoter-specific trans-activating transcription factor. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.
UniGene ID: Hs.444279
HGNC ID: HGNC:29520