human SDHC shRNA silencing AAV

Cat. No: shAAV-214170

Availability: 4-5 weeks

Name: AAV-h-SDHC-shRNA

This is an AAV expressing shRNA for silencing of Human SDHC.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SDHC
Gene Name: succinate dehydrogenase complex subunit C
Gene ID: 6391
Gene Synonyms: CYB560; CYBL; PGL3; QPS1; SDH3
ORF Size: 510 bp
RefSeq#: NM_003001
Gene Description: SDHC encodes one of four nuclear-encoded subunits that comprise succinate dehydrogenase, also known as mitochondrial complex II, a key enzyme complex of the tricarboxylic acid cycle and aerobic respiratory chains of mitochondria. The encoded protein is one of two integral membrane proteins that anchor other subunits of the complex, which form the catalytic core, to the inner mitochondrial membrane. Several related pseudogenes are located in different genomic regions. Mutations in this gene have been associated with paragangliomas. Alternatively spliced transcript variants encoding different isoforms have been described.
UniGene ID: Hs.444472
HGNC ID: HGNC:10682