human LMO2 shRNA silencing AAV

Cat. No: shAAV-214037

Availability: 6-8 weeks

Name: AAV-h-LMO2-shRNA

This is an AAV expressing shRNA for silencing of Human LMO2.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: LMO2
Gene Name: LIM domain only 2
Gene ID: 4005
Gene Synonyms: RBTN2; RBTNL1; RHOM2; TTG2
ORF Size: 456 bp
RefSeq#: NM_005574
Gene Description: LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms.
UniGene ID: Hs.716597
HGNC ID: HGNC:6642