human LGALS3 shRNA silencing AAV

Cat. No: shAAV-213851

Availability: 4-5 weeks

Name: AAV-h-LGALS3-shRNA

This is an AAV expressing shRNA for silencing of Human LGALS3.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: LGALS3
Gene Name: galectin 3
Gene ID: 3958
Gene Synonyms: CBP35; GAL3; GALBP; GALIG; L31; LGALS2; MAC2
ORF Size: 753 bp
RefSeq#: NM_002306
Gene Description: LGALS3 encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. Alternate splicing results in multiple transcript variants.
UniGene ID: Hs.531081
HGNC ID: HGNC:6563