human KRT8 shRNA silencing AAV

Cat. No: shAAV-213459

Availability: 6-8 weeks

Name: AAV-h-KRT8-shRNA

This is an AAV expressing shRNA for silencing of Human KRT8.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: KRT8
Gene Name: keratin 8
Gene ID: 3856
Gene Synonyms: CARD2; CK-8; CK8; CYK8; K2C8; K8; KO
ORF Size: 840 bp
RefSeq#: NM_002273
Gene Description: KRT8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.
UniGene ID: Hs.533782
HGNC ID: HGNC:6446