human KRT1 shRNA silencing AAV

Cat. No: shAAV-213373

Availability: 6-8 weeks

Name: AAV-h-KRT1-shRNA

This is an AAV expressing shRNA for silencing of Human KRT1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: KRT1
Gene Name: keratin 1
Gene ID: 3848
Gene Synonyms: CK1; EHK; EHK1; EPPK; K1; KRT1A; NEPPK
ORF Size: 1935 bp
RefSeq#: NM_006121
Gene Description: KRT1 is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
UniGene ID: Hs.80828
HGNC ID: HGNC:6412