human KLRD1 shRNA silencing AAV

Cat. No: shAAV-213324

Availability: 6-8 weeks

Name: AAV-h-KLRD1-shRNA

This is an AAV expressing shRNA for silencing of Human KLRD1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: KLRD1
Gene Name: killer cell lectin like receptor D1
Gene ID: 3824
Gene Synonyms: CD94
ORF Size: 540 bp
RefSeq#: NM_002262
Gene Description: Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. Three transcript variants encoding two different isoforms have been found for this gene.
UniGene ID: Hs.562457
HGNC ID: HGNC:6378