human KLK13 shRNA silencing AAV

Cat. No: shAAV-213280

Availability: 6-8 weeks

Name: AAV-h-KLK13-shRNA

This is an AAV expressing shRNA for silencing of Human KLK13.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: KLK13
Gene Name: kallikrein related peptidase 13
Gene ID: 26085
Gene Synonyms: KLK-L4; KLKL4
ORF Size: 834 bp
RefSeq#: NM_015596
Gene Description: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Expression of this gene is regulated by steroid hormones and may be useful as a marker for breast cancer. An additional transcript variant has been identified, but its full length sequence has not been determined.
UniGene ID: Hs.165296
HGNC ID: HGNC:6361